Molecular characteristics and phylogenetic analysis of novel goose parvovirus strains associated with short beak and dwarfism syndrome

Short beak and dwarfism syndrome (SBDS) emerged in Cherry Valley duck flocks China 2015, novel goose parvovirus (NGPV) was shown to be the etiological agent of SBDS. To date, it is not known whether SBDS-related NGPV isolates possess common molecular characteristics. In this study, three new strains (namely, SDHT16, SDJN19, SDLC19) were isolated from diseased ducks showing typical signs SBDS successfully passaged embryonated or eggs. The complete genome sequences these 98.9%–99.7% identical each other but showed slightly less similarity (95.2%–96.1% identity) classical GPV strains. A total 16 amino acid substitutions present VP1 proteins six (SDHT16, SDLC19, QH, JS1, SDLC01) compared with Chinese strains, nine which those found European strain B. non-structural protein Rep1 had 12 Phylogenetic analysis indicated that clustered forming a separate branch distinct group formed by study shows characteristics suggests probably share ancestor